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Higher cAMP activates protein kinase A
This may be due to reduced neutrophil infiltration, matrix metalloproteinase 9 (MMP9) levels, and cysteine availability, which impaired the synthesis of collagen, secreted protein acidic and rich in cysteine (SPARC), and cysteinyl leukotrienes, all of which contribute to fibrotic remodeling [126]
doi: 10.3389/fpsyt.2021.669089 35 CazzolaM.RoglianiP.SalviS
G., & Sterne, J
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